Structural Dynamics and Molecular Evolution of the SARS-CoV-2 Spike Protein-Reference-Cited by-同舟云学术

Structural Dynamics and Molecular Evolution of the SARS-CoV-2 Spike Protein

Published:2022-04-26 Issue:2 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Wolf Kyle A.¹²,Kwan Jason C.¹^ORCID,Kamil Jeremy P.³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA

2. Interdiscipinary Ph.D. Program in Structural and Computational Biology and Quantitative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin, USA

3. Department of Microbiology and Immunology, Louisiana State University Health Shreveport, Shreveport, Louisiana, USA

4. Center for Excellence in Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, Louisiana, USA

Abstract

The ongoing coronavirus disease 2019 (COVID-19) pandemic demonstrates the threat posed by novel coronaviruses to human health. Coronaviruses share a highly conserved cell entry mechanism mediated by the spike protein, the sole product of the S gene.

Funder

Emergent Ventures at the Mercatus Center, George Mason University

NIH

National Science Foundation

Rockefeller Foundation

NIH | NIGMS

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02030-21