Affiliation:
1. Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303.
Abstract
We characterized the genetic defect of a capsule-deficient serogroup B meningococcal strain created by Tn916 mutagenesis. The transposon insertion interrupts a capsule biosynthesis gene, synX, which is involved in the production of N-acetyl-D-mannosamine, a precursor of the (alpha 2-->8)-linked polysialic acid capsule of serogroup B meningococci.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
36 articles.
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