SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells-Reference-Cited by-同舟云学术

SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells

Published:2022-06-08 Issue:11 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Nchioua Rayhane¹,Schundner Annika²,Kmiec Dorota¹,Prelli Bozzo Caterina¹,Zech Fabian¹,Koepke Lennart¹,Graf Alexander³,Krebs Stefan³,Blum Helmut³,Frick Manfred²,Sparrer Konstantin M. J.¹,Kirchhoff Frank¹^ORCID

Affiliation:

1. Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany

2. Institute of General Physiology, Ulm University Medical Center, Ulm, Germany

3. Laboratory for Functional Genome Analysis, Gene Center, LMU München, Munich, Germany

Abstract

Recent data indicate that SARS-CoV-2 requires endogenously expressed IFITM proteins for efficient infection. However, the results were obtained with an early SARS-CoV-2 isolate.

Funder

Bundesministerium für Bildung und Forschung

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00594-22

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