Human Papillomavirus 31 Tyrosine 102 Regulates Interaction with E2 Binding Partners and Episomal Maintenance-Reference-Cited by-同舟云学术

Human Papillomavirus 31 Tyrosine 102 Regulates Interaction with E2 Binding Partners and Episomal Maintenance

Published:2020-07-30 Issue:16 Volume:94 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Gilson Timra¹,Culleton Sara²,Xie Fang³,DeSmet Marsha¹,Androphy Elliot J.¹²^ORCID

Affiliation:

1. Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA

2. Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA

3. Department of Dermatology, Chinese People’s Liberation Army General Hospital, Beijing, China

Abstract

Posttranslational modifications by phosphorylation can change protein activities, binding partners, or localization. Tyrosine 102 is conserved between delta papillomavirus BPV-1 and alpha papillomavirus HPV-31 E2. We characterized mutations of HPV-31 E2 for interactions with relevant cellular binding partners and replication in the context of the viral genome.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00590-20

Reference50 articles.

1. The Papillomavirus E2 proteins

2. Tumor suppressor or oncogene? A critical role of the human papillomavirus (HPV) E2 protein in cervical cancer progression;Bellanger S;Am J Cancer Res,2011

3. Phosphorylation sites of the E2 transcriptional regulatory proteins of bovine papillomavirus type 1

4. Bovine papillomavirus with a mutation in the E2 serine 301 phosphorylation site replicates at a high copy number

5. Characterization of Human Papillomavirus Type 16 E2 Protein and Subdomains Expressed in Insect Cells

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Human Papillomavirus Genome Copy Number Is Maintained by S-Phase Amplification, Genome Loss to the Cytosol during Mitosis, and Degradation in G ₁ Phase;Journal of Virology;2023-02-28

2. Effects of Caffeine, a DNA Damage Response Inhibitor, on Papillomavirus Genome Replication;Pathogens;2022-11-05

3. Human Papillomavirus Genome Copy Number Is Maintained by S Phase Amplification, Leakage to the Cytosol during Mitosis and Lysosomal Degradation in G1 Phase;2022-06-25

4. Regulation of the Human Papillomavirus Lifecyle through Post-Translational Modifications of the Viral E2 Protein;Pathogens;2021-06-23

5. Pyk2 Regulates Human Papillomavirus Replication by Tyrosine Phosphorylation of the E2 Protein;Journal of Virology;2020-09-29