The Interleukin-33–Group 2 Innate Lymphoid Cell Axis Represents a Potential Adjuvant Target To Increase the Cross-Protective Efficacy of Influenza Vaccine-Reference-Cited by-同舟云学术

The Interleukin-33–Group 2 Innate Lymphoid Cell Axis Represents a Potential Adjuvant Target To Increase the Cross-Protective Efficacy of Influenza Vaccine

Published:2021-10-27 Issue:22 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Williams Clare M.¹,Roy Sreeja¹,Califano Danielle¹,McKenzie Andrew N. J.²,Metzger Dennis W.¹,Furuya Yoichi¹^ORCID

Affiliation:

1. Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York, USA

2. Medical Research Council, Laboratory of Molecular Biology, Cambridge, Cambridgeshire, United Kingdom

Abstract

Current influenza vaccines, although capable of protecting against predicted viruses/strains included in the vaccine, are inept at providing cross-protection against emerging/novel strains. Thus, we are in critical need of a universal vaccine that can protect against a wide range of influenza viruses.

Funder

American Association of Immunologists

American Heart Association

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00598-21

Reference48 articles.

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2. Brief History and Characterization of Enhanced Respiratory Syncytial Virus Disease

3. Group 2 Innate Lymphoid Cell Production of IL-5 Is Regulated by NKT Cells during Influenza Virus Infection

4. Infection with Influenza Virus Induces IL-33 in Murine Lungs

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