Characterization of IS 6110 Restriction Fragment Length Polymorphism Patterns and Mechanisms of Antimicrobial Resistance for Multidrug-Resistant Isolates of Mycobacterium tuberculosis from a Major Reference Hospital in Assiut, Egypt-Reference-Cited by-同舟云学术

Characterization of IS 6110 Restriction Fragment Length Polymorphism Patterns and Mechanisms of Antimicrobial Resistance for Multidrug-Resistant Isolates of Mycobacterium tuberculosis from a Major Reference Hospital in Assiut, Egypt

Published:2001-06 Issue:6 Volume:39 Page:2330-2334
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Abbadi Said¹,Rashed Heba G.²,Morlock Glenn P.¹,Woodley Charles L.¹,El Shanawy O.²,Cooksey Robert C.¹

Affiliation:

1. Division of AIDS, STD, and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333,1and

2. Assiut University Hospital, Assiut, Egypt2

Abstract

ABSTRACT We evaluated 25 Mycobacterium tuberculosis isolates from patients at a major Egyptian reference hospital in Assiut, Egypt, who had been treated for at least 1 year for tuberculosis. Typing patterns (IS 6110 ) were diverse, and multidrug resistance was found among 11 (44%) of the isolates. Mutations associated with antimicrobial drug resistance were found in rpoB, katG, rpsL, and embB in the resistant isolates.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.39.6.2330-2334.2001

Reference16 articles.

1. Characterization of streptomycin resistance mechanisms among Mycobacterium tuberculosis isolates from patients in New York City

2. Comparison of two nonradioactive, single-strand conformation polymorphism electrophoretic methods for identification of rpoB mutations in rifampin-resistant Mycobacterium tuberculosis;Cooksey R. C.;Mol. Diagn.,1998

3. Elmoghazy E. National tuberculosis program report epidemiological review and action plan. 1997 Egyptian Ministry of Health Cairo Egypt

4. A continuing survey of drug-resistant tuberculosis, New York, April 1994;Fujiwara P. I.;Arch. Intern. Med.,1997

5. Streptomycin resistance in mycobacteria

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. How do Mutations of Mycobacterium Genes Cause Drug Resistance in Tuberculosis?;Current Pharmaceutical Biotechnology;2023-10-06

2. Molecular epidemiology of drug resistant Mycobacterium tuberculosis in Africa: a systematic review;BMC Infectious Diseases;2020-05-13

3. Detection of resistant strains of tubercle bacilli by gene mutation hybridization;The Egyptian Journal of Chest Diseases and Tuberculosis;2019

4. Comparison of PFGE, IS6110-RFLP, and 24-Locus MIRU-VNTR for Molecular Epidemiologic Typing of Mycobacterium tuberculosis Isolates with Known Epidemic Connections;Journal of Microbiology and Biotechnology;2018-02-28

5. Genotypic characterization of rpoB, katG and inhA gene of multi drug tuberculosis isolates from extra pulmonary tuberculosis;Biomedical and Biotechnology Research Journal (BBRJ);2017