Analysis of Invasive Nontypeable Haemophilus influenzae Isolates Reveals Selection for the Expression State of Particular Phase-Variable Lipooligosaccharide Biosynthetic Genes

Author:

Phillips Zachary N.1,Brizuela Charles1,Jennison Amy V.2ORCID,Staples Megan2,Grimwood Keith34,Seib Kate L.1ORCID,Jennings Michael P.1,Atack John M.1ORCID

Affiliation:

1. Institute for Glycomics, Griffith University, Gold Coast, Queensland, Australia

2. Public Health Microbiology, Forensic and Scientific Services, Queensland Department of Health, Brisbane, Queensland, Australia

3. Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia

4. Department of Infectious Diseases, Gold Coast Health, Gold Coast, Queensland, Australia

Abstract

Nontypeable Haemophilus influenzae (NTHi) is a major human pathogen, responsible for several acute and chronic infections of the respiratory tract. The incidence of invasive infections caused by NTHi is increasing worldwide.

Funder

Department of Health | National Health and Medical Research Council

Department of Education and Training | Australian Research Council

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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