Immunizations with Enterotoxigenic Escherichia coli Heat-Stable Toxin Conjugates Engender Toxin-Neutralizing Antibodies in Mice That Also Cross-React with Guanylin and Uroguanylin-Reference-Cited by-同舟云学术

Immunizations with Enterotoxigenic Escherichia coli Heat-Stable Toxin Conjugates Engender Toxin-Neutralizing Antibodies in Mice That Also Cross-React with Guanylin and Uroguanylin

Published:2019-07 Issue:7 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Diaz Yuleima¹,Govasli Morten L.¹,Zegeye Ephrem Debebe¹,Sommerfelt Halvor²³,Steinsland Hans²⁴,Puntervoll Pål¹²

Affiliation:

1. NORCE Norwegian Research Centre, Bergen, Norway

2. Centre for Intervention Science in Maternal and Child Health, Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway

3. Division of Infectious Disease Control, Norwegian Institute of Public Health, Oslo, Norway

4. Department of Biomedicine, University of Bergen, Bergen, Norway

Abstract

Infection with enterotoxigenic Escherichia coli (ETEC) is a common cause of childhood diarrhea in low- and middle-income countries, as well as of diarrhea among travelers to these countries. In children, ETEC strains secreting the heat-stable toxin (ST) are the most pathogenic, and there are ongoing efforts to develop vaccines that target ST.

Funder

Norges Forskningsråd

PATH

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00099-19

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