Protection against herpes simplex virus infection in mice by Corynebacterium parvum

Author:

Kirchner H,Hirt H M,Munk K

Abstract

Corynebacterium parvum administered in mice prior to herpes simplex virus (HSV) infection significantly protected them against lethal encephalitis. This was seen both with a mouse strain highly susceptible to HSV and with one relatively resistant to HSV. Mice immunosuppressed by cyclophosphamide and showing an increased mortality after HSV infection were also protected by C. parvum pretreatment. However, C. parvum given simultaneously with or after HSV infection did not exert a therapeutic effect.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference13 articles.

1. On the role of mononuclear phagocytes in immunity against viruses;Allison A. C.;Prog. Med. Virol.,1974

2. Encephalitis caused by herpes-simplex virus;Editorial;N. Engl. J. Med.,1967

3. Halpern B. A. Fray Y. Crepin 0. Platica A. M. Lorinet A. Rabourdin L. Sparros and R. Isac. 1973. Corynebacterium parvum a potent immunostimulant in experimental infections and in malignancies p. 217-236. In G. E. W. Wolstenholm and J. Knight (ed.) Immunopotentiation Ciba Foundation Symp. 18 (new series). Associated Scientific Publishers London.

4. Herpes simplex vaccines;Hilleman M. R.;Cancer Res.,1976

5. Le Corynebacterium parvum dans les cancers avanc 6s;Israel L.;Nouv. Presse Med.,1972

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