Activity of Chitosan and Its Derivatives against Leishmania major and Leishmania mexicana In Vitro-Reference-Cited by-同舟云学术

Activity of Chitosan and Its Derivatives against Leishmania major and Leishmania mexicana In Vitro

Published:2020-02-21 Issue:3 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Riezk Alaa¹,Raynes John G.¹,Yardley Vanessa¹,Murdan Sudaxshina²,Croft Simon L.¹

Affiliation:

1. Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom

2. Department of Pharmaceutics, UCL School of Pharmacy, University College London, London, United Kingdom

Abstract

There is an urgent need for safe, efficacious, affordable, and field-adapted drugs for the treatment of cutaneous leishmaniasis, which newly affects around 1.5 million people worldwide annually. Chitosan, a biodegradable cationic polysaccharide, has previously been reported to have antimicrobial, antileishmanial, and immunostimulatory activities.

Funder

Council for At-Risk Academics (CARA) UK

London School of Hygiene and Tropical Medicine

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01772-19

Reference74 articles.

1. Cutaneous leishmaniasis

2. Leishmaniasis Worldwide and Global Estimates of Its Incidence