Antigenemia in Patients with Mediterranean Visceral Leishmaniasis-Reference-Cited by-同舟云学术

Antigenemia in Patients with Mediterranean Visceral Leishmaniasis

Published:2009-11 Issue:11 Volume:47 Page:3760-3762
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Ferrua Bernard¹²,Rol Nicolas¹,Michel Grégory¹²,Marty Pierre¹²³

Affiliation:

1. Université de Nice Sophia Antipolis, Faculté de Médecine, Nice F-06107 Cedex 2, France

2. INSERM, U895, Centre Méditerranéen de Médecine Moléculaire (C3M), Equipe 6, Toxines Microbiennes dans la Relation Hôte-Pathogène, Nice F-06204 Cedex 3, France

3. Centre Hospitalier Universitaire de Nice, Laboratoire de Parasitologie-Mycologie, Nice F-06202 Cedex 3, France

Abstract

ABSTRACT Antigenemia in patients with Mediterranean visceral leishmaniasis (MVL) due to Leishmania infantum was retrospectively assessed by sandwich enzyme-linked immunosorbent assay (ELISA). Circulating Leishmania antigens, partially in free form, were in evidence in 53% of serum samples from immunocompetent individuals with MVL. Following successful therapy, antigenemia decline as measured by ELISA was more pronounced than antibody decrease.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00649-09

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