Complete Genome Sequence of a Parabacteroides distasonis Strain (CavFT hAR46) Isolated from a Gut Wall-Cavitating Microlesion in a Patient with Severe Crohn’s Disease

Author:

Yang Falong12,Kumar Anand3ORCID,Davenport Karen Walston3,Kelliher Julia Mae3,Ezeji Jessica C.12,Good Caryn E.4,Jacobs Michael R.45,Conger Mathew12,West Gail6,Fiocchi Claudio6,Cominelli Fabio157,Dichosa Armand Earl Ko3,Rodriguez-Palacios Alexander12ORCID

Affiliation:

1. Division of Gastroenterology & Liver Disease, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

2. Digestive Research Health Institute, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

3. B-10, Biosecurity and Public Health, Los Alamos National Laboratory, Los Alamos, New Mexico, USA

4. Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA

5. Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA

6. Department of Inflammation and Immunity, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, USA

7. Digestive Health Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA

Abstract

Crohn’s disease (CD) is a chronic inflammatory bowel disease (IBD) of the digestive tract in humans. There is evidence that Parabacteroides distasonis could contribute to IBD. Here, we present the complete genome sequence of a strain designated CavFT-hAR46, which was isolated from a gut intramural cavernous fistulous tract (CavFT) microlesion in a CD patient.

Funder

NIH NIDDK R21

HHS | NIH | NIH Clinical Center

DOE | LDRD | Los Alamos National Laboratory

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

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