Comparative In Vitro Efficacies of Various Catheter Lock Solutions-Reference-Cited by-同舟云学术

Comparative In Vitro Efficacies of Various Catheter Lock Solutions

Published:2006-05 Issue:5 Volume:50 Page:1865-1868
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Sherertz Robert J.¹,Boger Michael S.¹,Collins Casey A.¹,Mason Lori²,Raad Issam I.³

Affiliation:

1. Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina

2. Department of Infection Control, North Carolina Baptist Hospital, Winston-Salem, North Carolina

3. Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M. D. Anderson Cancer Center, Houston, Texas

Abstract

ABSTRACT MEDTA (minocycline-edetate calcium disodium), taurolidine (2%)-polyvinylpyrolidine (5%) (T/PVP), and ethanol as potential catheter lock solutions have a unique mechanism of action, broad-spectrum activity, and anticoagulant properties. Traditional lock solutions minocycline (M), rifampin (R), ciprofloxacin (C), and vancomycin, except pharmacologic concentrations of C and R and of M and R, were less effective than MEDTA and T/PVP.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.50.5.1865-1868.2006

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