Constitutive Differences in Gene Expression Profiles Parallel Genetic Patterns of Susceptibility to Tuberculosis in Mice-Reference-Cited by-同舟云学术

Constitutive Differences in Gene Expression Profiles Parallel Genetic Patterns of Susceptibility to Tuberculosis in Mice

Published:2006-06 Issue:6 Volume:74 Page:3668-3672
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Orlova Marianna O.¹²,Majorov Konstantin B.¹,Lyadova Irina V.¹,Eruslanov Eugenii B.¹,M'lan Cyr E.³,Greenwood Celia M. T.³,Schurr Erwin²,Apt Alexander S.¹

Affiliation:

1. Laboratory for Immunogenetics, Central Institute for Tuberculosis, Yauza Alley 2, Moscow 107564, Russia

2. McGill Centre for the Study of Host Resistance, Research Institute of the McGill University Health Centre, Montreal, H3G 1A4 Quebec, Canada

3. Program in Genetics and Genomic Biology, Hospital for Sick Children Research Institute, Toronto, Ontario, Canada

Abstract

ABSTRACT Interstitial lung macrophages from tuberculosis-susceptible I/St and tuberculosis-resistant A/Sn mice demonstrated significant constitutive differences in gene expression levels, whereas in vitro infection of these cells with Mycobacterium tuberculosis had only a modulatory impact on gene expression. We conclude that intrinsic gene expression profiles are an important determinant of tuberculosis pathogenesis in mice.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00196-06

Reference28 articles.

1. Bartz, H., F. Buning-Pfaue, O. Turkel, and U. Schauer. 2002. Respiratory syncytial virus induces prostaglandin E2, IL-10 and IL-11 generation in antigen presenting cells. Clin. Exp. Immunol.129:438-445.

2. Carlsen, H. S., E. S. Baekkevold, H. C. Morton, G. Haraldsen, and P. Brandtzaeg. 2004. Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis. Blood104:3021-3027.

3. Cupedo, T., F. E. Lund, V. N. Ngo, T. D. Randall, W. Jansen, M. J. Greuter, R. de Waal-Malefyt, G. Kraal, J. G. Cyster, and R. E. Mebius. 2004. Initiation of cellular organization in lymph nodes is regulated by non-B cell-derived signals and is not dependent on CXC chemokine ligand 13. J. Immunol.173:4889-4896.

4. Ehrt, S., D. Schnappinger, S. Bekiranov, J. Drenkow, S. Shi, T. R. Gingeras, T. Gaasterland, G. Schoolnik, and C. Nathan. 2001. Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase. J. Exp. Med.194:1123-1140.

5. Elias, J. A., T. Zheng, N. L. Whiting, T. K. Trow, W. W. Merrill, R. Zitnik, P. Ray, and E. M. Alterman. 1994. IL-1 and transforming growth factor-beta regulation of fibroblast-derived IL-11. J. Immunol.152:2421-2429.

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