Affiliation:
1. Departments of Medical Microbiology, Surgery, and Pediatrics, University of Wisconsin Medical School, Madison, Wisconsin 53706
Abstract
Cellulose-acetate and agar gel immunoelectrophoresis were used to study the serum protein patterns of germfree rats before and after monoassociation with a pure culture of
Staphylococcus aureus
(phage type 80/81),
Streptococcus faecalis, Lactobacillus acidophilus, Bacteroides fragilis, Pseudomonas aeruginosa
, or
Proteus vulgaris.
All six bacteria quickly established themselves in the gastrointestinal tract of the germfree rat, and all six increased the animals' total serum proteins. Only
S. aureus
and
P. aeruginosa
caused a noticeable rise in gamma globulins.
L. acidophilus, S. faecalis
, and
B. fragilis
multiplied readily in the gastrointestinal tract but caused only minimal alterations in the serum proteins.
P. vulgaris
caused a marked increase in the alpha and beta, but not the gamma globulins.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
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