Dendritic Cells Can Initiate Protective Immune Responses against Malaria-Reference-Cited by-同舟云学术

Dendritic Cells Can Initiate Protective Immune Responses against Malaria

Published:2001-08 Issue:8 Volume:69 Page:5173-5176
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Bruña-Romero Oscar¹,Rodriguez Ana¹

Affiliation:

1. Department of Medical and Molecular Parasitology, New York University School of Medicine, New York, New York 10010

Abstract

ABSTRACT An understanding of the antigen presentation mechanisms that mediate induction of protective immune responses against malaria is essential for the development of successful immunization approaches. Here we show that dendritic cells presenting Plasmodium yoelii sporozoite antigens are able to activate specific CD4 + and CD8 + T cells and initiate protective immune responses against malaria in mice.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.69.8.5173-5176.2001

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