Antibiotics Stimulate Formation of Vesicles in Staphylococcus aureus in both Phage-Dependent and -Independent Fashions and via Different Routes

Author:

Andreoni Federica1,Toyofuku Masanori23,Menzi Carmen1,Kalawong Ratchara3,Mairpady Shambat Srikanth1,François Patrice4,Zinkernagel Annelies S.1ORCID,Eberl Leo3ORCID

Affiliation:

1. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland

2. Department of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan

3. Department of Plant and Microbial Biology, University of Zurich, Zurich, Switzerland

4. Laboratoire de Recherche Génomique, Service des Maladies Infectieuses, Centre Médical Universitaire, Geneva, Switzerland

Abstract

Bacterial membrane vesicle research has so far focused mainly on Gram-negative bacteria. Only recently have Gram-positive bacteria been demonstrated to produce and release extracellular membrane vesicles (MVs) that contribute to bacterial virulence.

Funder

JST ERATO

Swiss National Foundation

JSPS KAKENHI

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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