In Vivo Pharmacodynamic Characterization of a Novel Plectasin Antibiotic, NZ2114, in a Murine Infection Model
Author:
Affiliation:
1. Departments of Medicine
2. Medical Microbiology and Immunology, University of Wisconsin, 600 Highland Ave, Room H4/572, Madison, Wisconsin 53792
3. Novozymes A/S, Krogshoejvej 36, 2880 Bagsvaerd, Denmark
Abstract
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Link
https://journals.asm.org/doi/pdf/10.1128/AAC.01584-08
Reference17 articles.
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2. Ambrose, P. G., J. B. Anon, S. M. Bhavnani, O. O. Okusanya, R. N. Jones, M. R. Paglia, J. Kahn, and G. L. Drusano. 2008. Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis. Diagn. Microbiol. Infect. Dis.61:13-20.
3. Andes, D., and W. A. Craig. 2002. Animal model pharmacokinetics and pharmacodynamics: a critical review. Int. J. Antimicrob. Agents19:261-268.
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