The Compact Macronuclear Genome of the Ciliate Halteria grandinella: A Transcriptome-Like Genome with 23,000 Nanochromosomes-Reference-Cited by-同舟云学术

The Compact Macronuclear Genome of the Ciliate Halteria grandinella: A Transcriptome-Like Genome with 23,000 Nanochromosomes

Published:2021-02-23 Issue:1 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Zheng Weibo¹²³,Wang Chundi¹,Lynch Michael²,Gao Shan¹⁴^ORCID

Affiliation:

1. Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China

2. Biodesign Institute, Center for Mechanisms of Evolution, Arizona State University, Tempe, Arizona, USA

3. School of Life Sciences, Ludong University, Yanti, China

4. Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China

Abstract

How to achieve protein diversity by genome and transcriptome processing is essential for organismal complexity and adaptation. The present work identifies that the macronuclear genome of Halteria grandinella , a cosmopolitan unicellular eukaryote, is composed almost entirely of gene-sized nanochromosomes with extremely short nongenic regions.

Funder

The Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology

National Institute of Health Grant

National Science Foundation

MOE | Fundamental Research Funds for the Central Universities

Taishan Scholar Program of Shandong Province

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.01964-20