A Unique Reverse Adaptation Mechanism Assists Bordetella pertussis in Resistance to Both Scarcity and Toxicity of Manganese-Reference-Cited by-同舟云学术

A Unique Reverse Adaptation Mechanism Assists Bordetella pertussis in Resistance to Both Scarcity and Toxicity of Manganese

Published:2021-10-26 Issue:5 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Čapek Jan¹^ORCID,Procházková Ilona¹^ORCID,Matoušek Tomáš²^ORCID,Hot David³^ORCID,Večerek Branislav¹^ORCID

Affiliation:

1. Laboratory of Post-transcriptional Control of Gene Expression, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic

2. Institute of Analytical Chemistry of the Czech Academy of Sciences, Brno, Czech Republic

3. CHU Lille, Institut Pasteur de Lille, Inserm, CNRS, UMR2014—US41—PLBS Plateformes Lilloises de Biologie & Santé, Université de Lille, Lille, France

Abstract

Bordetella pertussis , a respiratory pathogen restricted to humans, continuously adapts its genome to its exclusive host. We show that speciation of this reemerging pathogen was accompanied by loss of function of the manganese exporter.

Funder

The Czech Science Foundation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.01902-21

Reference68 articles.

1. Transition Metals and Virulence in Bacteria

2. Metallobiology of host–pathogen interactions: an intoxicating new insight

3. Nutritional Immunity

4. Nutritional immunity beyond iron: a role for manganese and zinc

5. Emerging themes in manganese transport, biochemistry and pathogenesis in bacteria

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Why is manganese so valuable to bacterial pathogens?;Frontiers in Cellular and Infection Microbiology;2023-02-03

2. Avirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment;Emerging Microbes & Infections;2023-01-19

3. Conquering the host: Bordetella spp. and Pseudomonas aeruginosa molecular regulators in lung infection;Frontiers in Microbiology;2022-09-26