Immunogenicity of HIV Virus-Like Particles in Rhesus Macaques by Intranasal Administration-Reference-Cited by-同舟云学术

Immunogenicity of HIV Virus-Like Particles in Rhesus Macaques by Intranasal Administration

Published:2012-06 Issue:6 Volume:19 Page:970-973
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Buonaguro Luigi¹,Tagliamonte Maria¹,Visciano Maria Luisa¹,Andersen Hanne²,Lewis Mark²,Pal Ranajit³,Tornesello Maria Lina¹,Schroeder Ulf⁴,Hinkula Jorma⁵,Wahren Britta⁶,Buonaguro Franco M.¹

Affiliation:

1. Laboratory of Molecular Biology and Viral Oncogenesis, Istituto Nazionale Tumori Fond. G. Pascale, Naples, Italy

2. Bioqual Inc., Rockville, Maryland, USA

3. Advanced BioScience Laboratories, Inc., Kensington, Maryland, USA

4. Eurocine Vaccines AB, Karolinska Institutet Science Park, Stockholm, Sweden

5. Department of Molecular Virology, Linköping University, Linköping, Sweden

6. Swedish Institute for Infectious Disease Control, Stockholm, Sweden

Abstract

ABSTRACT Female rhesus macaques were immunized with HIV virus-like particles (HIV-VLPs) or HIV DNA administered as sequential combinations of mucosal (intranasal) and systemic (intramuscular) routes, according to homologous or heterologous prime-boost schedules. The results show that in rhesus macaques only the sequential intranasal and intramuscular administration of HIV-VLPs, and not the intranasal alone, is able to elicit humoral immune response at the systemic as well as the vaginal level.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00068-12

Reference44 articles.

1. Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1;Alfsen A;J. Immunol.,2001

2. Intranasal administration of adjuvant-combined recombinant influenza virus HA vaccine protects mice from the lethal H5N1 virus infection

3. Protection of macaques against vaginal SHIV challenge by systemic or mucosal and systemic vaccinations with HIV-envelope;Barnett SW;AIDS,2008

4. A novel gp120 sequence from an HIV-1 isolate of the A clade identified in North Uganda;Buonaguro L;AIDS Res. Hum. Retroviruses,1998

5. High efficient production of Pr55gag virus-like particles expressing multiple HIV-1 epitopes, including a gp120 protein derived from an Ugandan HIV-1 isolate of subtype A;Buonaguro L;Antiviral Res.,2001

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