BioFire FilmArray Respiratory Panel for Detection of Enterovirus D68

Author:

Shibib Dena R.12,Matushek Scott M.1,Beavis Kathleen G.1,Gawel Susan H.3,Charnot-Katsikas Angella1

Affiliation:

1. The University of Chicago Medicine, Department of Pathology, Chicago, Illinois, USA

2. NorthShore University HealthSystem, Department of Pathology, Evanston, Illinois, USA

3. Northwestern University Feinberg School of Medicine, Department of Preventive Medicine, Chicago, Illinois, USA

Abstract

ABSTRACT During the enterovirus D68 (EV-D68) outbreak of 2014, the BioFire FilmArray (FA) respiratory panel was used to detect rhinovirus/enterovirus in respiratory specimens; suspected EV-D68-positive specimens were sent to CDC for confirmation. Positive rhinovirus/enterovirus FA targets revealed patterns loosely associated with EV-D68 that may be useful for confirmation triaging.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference14 articles.

1. Severe respiratory illness associated with enterovirus D68—Missouri and Illinois, 2014;Midgley CM;MMWR Morb Mortal Wkly Rep,2014

2. Global reemergence of enterovirus D68 as an important pathogen for acute respiratory infections

3. Worldwide emergence of multiple clades of enterovirus 68

4. Stellrecht KA, Lamson DM, Romero JR. 2011. Enteroviruses and parechoviruses, p 1388–1389. In Versalovic J, Carroll KC, Funke G, Jorgensen JH, Landry ML, Warnock DW (ed), Manual of clinical microbiology, 10th ed, vol 2. ASM Press, Washington, DC.

5. The 5'-untranslated regions of picornavirus RNAs contain independent functional domains essential for RNA replication and translation

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