Comparison of IsoCode STIX and FTA Gene Guard Collection Matrices as Whole-Blood Storage and Processing Devices for Diagnosis of Malaria by PCR-Reference-Cited by-同舟云学术

Comparison of IsoCode STIX and FTA Gene Guard Collection Matrices as Whole-Blood Storage and Processing Devices for Diagnosis of Malaria by PCR

Published:2001-03 Issue:3 Volume:39 Page:1195-1196
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Zhong Kathleen J. Y.¹,Salas Carola J.²,Shafer Robyn¹,Gubanov Alex¹,Gasser Robert A.³,Magill Alan J.²,Forney J. Russ⁴,Kain Kevin C.¹

Affiliation:

1. Centre for Travel and Tropical Medicine, Division of Infectious Diseases, Department of Medicine, Toronto General Hospital and the University of Toronto1;

2. Department of Parasitology, U.S. Naval Medical Research Center Detachment, Lima, Peru2; and

3. Department of Immunology3 and

4. Department of Parasitology,4 Walter Reed Army Institute of Research, Silver Spring, Maryland

Abstract

ABSTRACT We compared two collection devices, IsoCode and FTA, with whole blood for the diagnosis of malaria by PCR ( n = 100). Using whole blood as the reference standard, both devices were sensitive for the detection of single-species malaria infections by PCR (≥96%). However, the detection of mixed infections was suboptimal (IsoCode was 42% sensitive, and FTA was 63% sensitive).

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.39.3.1195-1196.2001

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