Antimicrobial Activity of CHIR-090, an Inhibitor of Lipopolysaccharide Biosynthesis, against the Burkholderia cepacia Complex-Reference-Cited by-同舟云学术

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Antimicrobial Activity of CHIR-090, an Inhibitor of Lipopolysaccharide Biosynthesis, against the Burkholderia cepacia Complex

Published:2010-08 Issue:8 Volume:54 Page:3531-3533
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Bodewits Karin¹,Raetz Christian R. H.²,Govan John R.³,Campopiano Dominic J.¹

Affiliation:

1. School of Chemistry  University of Edinburgh  Edinburgh EH9 3JJ, Scotland, United Kingdom

2. Department of Biochemistry  Duke University Medical Center  Durham, North Carolina 27710

3. Centre for Infectious Diseases  University of Edinburgh Medical School  Edinburgh EH16 4SB, Scotland, United Kingdom

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01600-09

Reference41 articles.

1. Antibacterial agents. 2004

2. Andrews, J. 2009. BSAC standardized disc susceptibility testing method (version 8). J. Antimicrob. Chemother.64:454-489.

3. Avgeri, S., D. Matthaiou, G. Dimopoulos, A. Grammatikos, and M. Falagas. 2009. Therapeutic options for Burkholderia cepacia infections beyond co-trimoxazole: a systematic review of the clinical evidence. Int. J. Antimicrob. Agents33:394-404.

4. Multilocus Sequence Typing Scheme That Provides Both Species and Strain Differentiation for the Burkholderia cepacia Complex

5. Barb, A. W., L. Jiang, C. R. Raetz, and P. Zhou. 2007. Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: time-dependent inhibition and specificity in ligand binding. Proc. Natl. Acad. Sci. U. S. A.104:18433-18438.

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3. Targeted lipopolysaccharide biosynthetic intermediate analysis with normal-phase liquid chromatography mass spectrometry;PLOS ONE;2019-02-08

4. Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis;mSphere;2018-10-31

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