Effect of NlpE Overproduction on Multidrug Resistance in Escherichia coli-Reference-Cited by-同舟云学术

Effect of NlpE Overproduction on Multidrug Resistance in Escherichia coli

Published:2010-05 Issue:5 Volume:54 Page:2239-2243
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Nishino Kunihiko¹²,Yamasaki Seiji¹³⁴,Hayashi-Nishino Mitsuko³,Yamaguchi Akihito³⁴

Affiliation:

1. Laboratory of Microbiology and Infectious Diseases

2. PRESTO, Japan Science and Technology Corporation, Tokyo 102-0075, Japan

3. Department of Cell Membrane Biology, Institute of Scientific and Industrial Research, Osaka University, Osaka 567-0047, Japan

4. School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan

Abstract

ABSTRACT NlpE, an outer membrane lipoprotein, functions during envelope stress responses in Gram-negative bacteria. In this study, we report that overproduction of NlpE increases multidrug and copper resistance through activation of the genes encoding the AcrD and MdtABC multidrug efflux pumps in Escherichia coli .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01677-09

Reference30 articles.

1. The Complete Genome Sequence of Escherichia coli K-12

2. Brown, M. H., I. T. Paulsen, and R. A. Skurray. 1999. The multidrug efflux protein NorM is a prototype of a new family of transporters. Mol. Microbiol.31:394-395.

3. Connolly, L., A. De Las Penas, B. M. Alba, and C. A. Gross. 1997. The response to extracytoplasmic stress in Escherichia coli is controlled by partially overlapping pathways. Genes Dev.11:2012-2021.

4. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

5. Genome-wide Profiling of Promoter Recognition by the Two-component Response Regulator CpxR-P in Escherichia coli

Cited by 42 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Intraspecific variation in antibiotic resistance potential within E. coli;Microbiology Spectrum;2024-06-04

2. Are envelope stress responses essential for persistence to β-lactams in Escherichia coli ?;Antimicrobial Agents and Chemotherapy;2023-10-18

3. A critical role of the periplasm in copper homeostasis in Gram-negative bacteria;Biosystems;2023-09

4. Drug resistance and physiological roles of RND multidrug efflux pumps in Salmonella enterica, Escherichia coli and Pseudomonas aeruginosa;Microbiology;2023-06-15

5. Residue Lys219 of CpxR is critical in the regulation of the antibiotic resistance of Escherichia coli;Journal of Antimicrobial Chemotherapy;2023-06-08