A Short-Tandem-Repeat Assay ( Mmy STR) for Studying Genetic Variation in Madurella mycetomatis

Author:

Nyuykonge Bertrand1ORCID,Eadie Kimberly1,Zandijk Willemien H. A.1,Ahmed Sarah A.23,Desnos-Ollivier Marie4ORCID,Fahal Ahmed H.5,de Hoog Sybren2,Verbon Annelies1,van de Sande Wendy W. J.1ORCID,Klaassen Corné H. W.1ORCID

Affiliation:

1. Erasmus MC University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases, Rotterdam, The Netherlands

2. Center of Expertise in Mycology of Radboud University Medical Center/Canisius Wilhelmina Hospital, Nijmegen, The Netherlands

3. Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum, Sudan

4. Institut Pasteur, CNRS UMR 2000, National Reference Center for Invasive Mycoses & Antifungals, Molecular Mycology Unit, Institut Pasteur, Paris, France

5. Mycetoma Research Center, Khartoum, Sudan

Abstract

Madurella mycetomatis is the major causative agent of eumycetoma, a neglected tropical infection characterized by painless subcutaneous lesions, inflammation, and grains draining from multiple sinuses. To study the epidemiology of mycetoma, a robust discriminatory typing technique is needed.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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