Effectiveness of a Double-Carbapenem Regimen for Infections in Humans Due to Carbapenemase-Producing Pandrug-Resistant Klebsiella pneumoniae-Reference-Cited by-同舟云学术

Effectiveness of a Double-Carbapenem Regimen for Infections in Humans Due to Carbapenemase-Producing Pandrug-Resistant Klebsiella pneumoniae

Published:2013-05 Issue:5 Volume:57 Page:2388-2390
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Giamarellou Helen¹,Galani Lambrini¹,Baziaka Fotini¹,Karaiskos Ilias¹

Affiliation:

1. 6th Department of Internal Medicine, Hygeia General Hospital, Athens, Greece

Abstract

ABSTRACT Ertapenem plus doripenem or meropenem were given in three patients suffering from pandrug-resistant, KPC-2-positive Klebsiella pneumoniae bacteremia (2 patients) and urinary tract infection (1 patient), respectively. All responded successfully, without relapse at follow-up. The results obtained should probably be attributed to ertapenem's increased affinity for the carbapenemases hindering doripenem/meropenem degradation in the environment of the microorganism.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02399-12

Reference13 articles.

1. Carbapenem resistance in Enterobacteriaceae: here is the storm!

2. Metallo-β-lactamases: a last frontier for β-lactams?;Cornaglia G;Lancet Infect. Dis.,2011

3. An update of the evolving epidemic of blaKPC-2-carrying Klebsiella pneumoniae in Greece (2009-10);Giakkoupi P;J. Antimicrob. Chemother.,2011

4. Interventional strategies and current clinical experience with carbapenemase-producing Gram-negative bacteria;Akova M;Clin. Microbiol. Infect.,2012

5. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance;Magiorakos AP;Clin. Microbiol. Infect.,2012

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