Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice-Reference-Cited by-同舟云学术

Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice

Published:1986-07 Issue:1 Volume:59 Page:168-171
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Nakanaga K,Yamanouchi K,Fujiwara K

Abstract

Neutralizing and nonneutralizing monoclonal antibodies to the peplomer glycoprotein and nucleocapsid protein of a mouse hepatitis virus (MHV), MHV-NuU, protected mice against lethal MHV-2 challenge. Histopathologically, livers of mice receiving protective antibodies showed some focal necrotic lesions with remarkable cellular infiltration instead of fulminant hepatitis caused by MHV-2.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.59.1.168-171.1986

Reference28 articles.

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