In vitro activity and beta-lactamase stability of a monobactam, SQ 26,917, compared with those of aztreonam and other agents

Author:

Neu H C,Labthavikul P

Abstract

SQ 26,917 is a monobactam antibiotic. Its in vitro activity was compared with those of aztreonam, cefotaxime, ceftazidime, and moxalactam. SQ 26,917, which contains a beta-methyl configuration on the beta-lactam ring, was similar in activity to aztreonam with the exception of greater activity against Pseudomonas aeruginosa isolates. SQ 26,917 had no activity against gram-positive isolates or anaerobic bacteria. It was not hydrolyzed by common plasmid and chromosomal beta-lactamases.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Cited by 27 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Antibacterial and β-Lactamase Inhibitory Activity of Monocyclic β-Lactams;Medicinal Research Reviews;2017-08-16

2. IN VITRO ACTIVITY OF CEFTAZIDIME, CEFOTAXIME AND GENTAMICIN AGAINST 11,521 CLINICAL ISOLATES OF BACTERIA;Acta Pathologica Microbiologica Scandinavica Series B: Microbiology;2009-08-15

3. Carbapenems and Monobactams: Imipenem, Meropenem, and Aztreonam;Mayo Clinic Proceedings;1999-04

4. Aztreonam;Medical Clinics of North America;1995

5. AMINOGLYCOSIDES, IMIPENEM, AND AZTREONAM;Clinics in Podiatric Medicine and Surgery;1992-04

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3