Biogenic Amines Increase the Odds of Bacterial Vaginosis and Affect the Growth of and Lactic Acid Production by Vaginal Lactobacillus spp.-Reference-Cited by-同舟云学术

Biogenic Amines Increase the Odds of Bacterial Vaginosis and Affect the Growth of and Lactic Acid Production by Vaginal Lactobacillus spp.

Published:2021-04-27 Issue:10 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Borgogna Joanna-Lynn C.¹²^ORCID,Shardell Michelle D.³⁴,Grace Savannah G.¹,Santori Elisa K.²,Americus Benjamin²,Li Zhong⁵,Ulanov Alexander⁵,Forney Larry⁶⁷^ORCID,Nelson Tiffanie M.¹²,Brotman Rebecca M.³⁴^ORCID,Ravel Jacques⁴⁸^ORCID,Yeoman Carl J.¹²^ORCID

Affiliation:

1. Department of Animal & Range Sciences, Montana State University, Bozeman, Montana, USA

2. Department of Microbiology & Immunology, Montana State University, Bozeman, Montana, USA

3. Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA

4. Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA

5. Roy J. Carver Biotechnology Center, University of Illinois, Urbana, Illinois, USA

6. Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, Idaho, USA

7. Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA

8. Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA

Abstract

Lactobacillus spp. are credited with providing the primary defense against gynecological conditions, including BV, most notably through the acidification of the vaginal microenvironment, which results from their production of lactic acid. The microbial production of BAs has been hypothesized to play a mechanistic role in diminishing Lactobacillus species-mediated protection, enabling the colonization and outgrowth of diverse anaerobic bacterial species associated with BV.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of General Medical Sciences

HHS | NIH | National Institute of Nursing Research

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.03068-20

Reference80 articles.

1. Vaginal biogenic amines: biomarkers of bacterial vaginosis or precursors to vaginal dysbiosis?