Triazole Priming as an Adaptive Response and Gateway to Resistance in Aspergillus fumigatus-Reference-Cited by-同舟云学术

Triazole Priming as an Adaptive Response and Gateway to Resistance in Aspergillus fumigatus

Published:2022-08-16 Issue:8 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Harish Ety¹,Sarkar Argha¹,Handelman Mariana¹,Abo Kandil Amar¹,Shadkchan Yana¹,Wurster Sebastian²^ORCID,Kontoyiannis Dimitrios P.²^ORCID,Osherov Nir¹^ORCID

Affiliation:

1. Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

2. Department of Infectious Diseases, Infection Control and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Abstract

Invasive aspergillosis (IA), caused predominantly by Aspergillus fumigatus , is the most common opportunistic mold infection in immunocompromised patients. Resistance of A. fumigatus to triazoles has been increasingly reported, leading to poor outcomes of IA to the front-line azoles.

Funder

Israel Academy of Sciences and Humanities

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.00458-22

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