Gamma Interferon and Interleukin-10 Gene Expression in Synovial Tissues from Patients with Early Stages of Chlamydia -Associated Arthritis and Undifferentiated Oligoarthritis and from Healthy Volunteers-Reference-Cited by-同舟云学术

Gamma Interferon and Interleukin-10 Gene Expression in Synovial Tissues from Patients with Early Stages of Chlamydia -Associated Arthritis and Undifferentiated Oligoarthritis and from Healthy Volunteers

Published:1999-05 Issue:5 Volume:67 Page:2682-2686
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Kotake Shigeru¹,Schumacher H. Ralph¹²,Arayssi Thurayya K.¹,Gérard Herve C.³,Branigan Patrick J.⁴,Hudson Alan P.³,Yarboro Cheryl H.¹,Klippel John H.¹,Wilder Ronald L.¹

Affiliation:

1. National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland1;

2. Department of Veterans Affairs Medical Center2 and

3. Department of Immunology and Microbiology, Wayne State University Medical School, Detroit, Michigan3

4. Department of Microbiology and Immunology, MCP-Hahnemann School of Medicine,4 Philadelphia, Pennsylvania; and

Abstract

ABSTRACT Genetically determined differences in interleukin-10 (IL-10) and gamma interferon (IFN-γ) responses in mice correlate with clearance of Chlamydia pneumonitis infection. We measured the synovial expression of IL-10 and IFN-γ and additional cytokine genes in patients who had recent-onset Chlamydia -associated arthritis (Chl-AA). IL-10 and IFN-γ mRNA were relatively abundant in recent-onset Chl-AA.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.67.5.2682-2686.1999

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