Population Pharmacokinetics and Pharmacodynamics of Itraconazole for Disseminated Infection Caused by Talaromyces marneffei-Reference-Cited by-同舟云学术

Population Pharmacokinetics and Pharmacodynamics of Itraconazole for Disseminated Infection Caused by Talaromyces marneffei

Published:2021-10-18 Issue:11 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Stott Katharine E.¹^ORCID,Le Thuy²³,Nguyen Thu²³,Whalley Sarah¹,Unsworth Jennifer¹,Ly Vo Trieu⁴⁵,Kolamunnage-Dona Ruwanthi⁶,Hope William¹⁷^ORCID

Affiliation:

1. Antimicrobial Pharmacodynamics and Therapeutics, Department of Molecular and Clinical Pharmacology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, United Kingdom

2. Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam

3. Division of Infectious Diseases and International Health, Duke University School of Medicine, Durham, North Carolina, USA

4. University of Medicine and Pharmacy at Ho Chi Minh city, Ho Chi Minh City, Vietnam

5. Hospital for Tropical diseases, Ho Chi Minh City, Vietnam

6. Department of Health Data Science, Institute of Population Health, University of Liverpool, Liverpool, United Kingdom

7. Liverpool Health Partners, Liverpool, United Kingdom

Abstract

First-line treatment of talaromycosis with amphotericin B deoxycholate (DAmB) is labor-intensive and toxic. Itraconazole is an appealing alternative antifungal agent.

Funder

Wellcome Trust through the Joint Global Health Trials Grant

Department for International Development

European Commission

HHS | National Institutes of Health

HHS | U.S. Food and Drug Administration

National Institute for Health Research

UKRI | Medical Research Council

Wellcome Trust

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00636-21

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