Identification of Oxygen-Independent Pathways for Pyridine Nucleotide and Coenzyme A Synthesis in Anaerobic Fungi by Expression of Candidate Genes in Yeast-Reference-Cited by-同舟云学术

Identification of Oxygen-Independent Pathways for Pyridine Nucleotide and Coenzyme A Synthesis in Anaerobic Fungi by Expression of Candidate Genes in Yeast

Published:2021-06-29 Issue:3 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Perli Thomas¹^ORCID,Vos Aurin M.¹,Bouwknegt Jonna¹^ORCID,Dekker Wijb J. C.¹,Wiersma Sanne J.¹^ORCID,Mooiman Christiaan¹,Ortiz-Merino Raúl A.¹^ORCID,Daran Jean-Marc¹^ORCID,Pronk Jack T.¹^ORCID

Affiliation:

1. Department of Biotechnology, Delft University of Technology, Delft, The Netherlands

Abstract

NAD (NAD + ) and coenzyme A (CoA) are central metabolic cofactors whose canonical biosynthesis pathways in fungi require oxygen. Anaerobic gut fungi of the Neocallimastigomycota phylum are unique eukaryotic organisms that adapted to anoxic environments.

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00967-21

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