Diversity and Within-Host Evolution of Leishmania donovani from Visceral Leishmaniasis Patients with and without HIV Coinfection in Northern Ethiopia

Author:

Franssen Susanne U.1,Takele Yegnasew23,Adem Emebet2,Sanders Mandy J.1,Müller Ingrid3,Kropf Pascale3,Cotton James A.1ORCID

Affiliation:

1. Wellcome Sanger Institute, Hinxton, United Kingdom

2. Leishmaniasis Research and Treatment Centre, University of Gondar, Gondar, Ethiopia

3. Department of Infectious Disease, Imperial College London, London, United Kingdom

Abstract

Visceral leishmaniasis (VL) is the second largest cause of deaths due to parasite infections and a growing problem in East Africa. In Ethiopia, it is particularly associated with migrant workers moving from regions of nonendemicity for seasonal agricultural work and is frequently found as a coinfection with HIV, which leads to frequent VL relapse following treatment.

Funder

Wellcome

UKRI | Biotechnology and Biological Sciences Research Council

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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