Peroxiredoxin Asp f3 Is Essential for Aspergillus fumigatus To Overcome Iron Limitation during Infection-Reference-Cited by-同舟云学术

Peroxiredoxin Asp f3 Is Essential for Aspergillus fumigatus To Overcome Iron Limitation during Infection

Published:2021-08-31 Issue:4 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Brantl Victor¹,Boysen Jana M.²³,Yap Annie⁴,Golubtsov Evgeny⁵,Ruf Dominik¹,Heinekamp Thorsten⁶,Straßburger Maria⁷,Dichtl Karl¹,Haas Hubertus⁴,Hillmann Falk²,Wagener Johannes¹⁵⁸^ORCID

Affiliation:

1. Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Medizinische Fakultät, LMU München, Munich, Germany

2. Evolution of Microbial Interactions, Leibniz Institute for Natural Product Research and Infection Biology—Hans Knöll Institute, Jena, Germany

3. Institute of Microbiology, Friedrich Schiller University Jena, Jena, Germany

4. Institute of Molecular Biology, Medical University of Innsbruck, Innsbruck, Austria

5. Institut für Hygiene und Mikrobiologie, Julius-Maximilians-Universität Würzburg, Würzburg, Germany

6. Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology—Hans Knöll Institute, Jena, Germany

7. Transfer Group Anti-infectives, Leibniz Institute for Natural Product Research and Infection Biology—Hans Knöll Institute, Jena, Germany

8. Department of Clinical Microbiology, School of Medicine, Trinity College Dublin, The University of Dublin, St James’s Hospital Campus, Dublin, Ireland

Abstract

Asp f3 is one of the most abundant proteins in the pathogenic mold Aspergillus fumigatus . It has an enigmatic multifaceted role as a fungal allergen, virulence factor, reactive oxygen species (ROS) scavenger, and vaccine candidate.

Funder

Deutsche Forschungsgemeinschaft

Austrian Science Fund

Verein zur Förderung von Wissenschaft und Forschung an der Medizinischen Fakultät der Ludwig-Maximilians-Universität München e.V.

Förderprogramm für Forschung und Lehre (FöFoLe) of the Medical Faculty of the LMU Munich

Graduate School of Life Sciences (GSLS) at the University of Würzburg

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00976-21