Affiliation:
1. Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA
Abstract
Mononegavirales
, known as nonsegmented negative-sense (NNS) RNA viruses, are a class of pathogenic and sometimes deadly viruses that include rabies virus (RABV), human respiratory syncytial virus (HRSV), and Ebola virus (EBOV). Unfortunately, no effective vaccines and antiviral therapeutics against many
Mononegavirales
are currently available. Viral polymerases have been attractive and major antiviral therapeutic targets. Therefore,
Mononegavirales
polymerases have been extensively investigated for their structures and functions.
Funder
HHS | NIH | National Institute of General Medical Sciences
Emory University | School of Medicine, Emory University
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Cited by
39 articles.
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