Borrelia burgdorferi bbk13 Is Critical for Spirochete Population Expansion in the Skin during Early Infection

Author:

Aranjuez George F.1ORCID,Kuhn Hunter W.1,Adams Philip P.1,Jewett Mollie W.1ORCID

Affiliation:

1. Division of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, Florida, USA

Abstract

Lyme disease is caused by the spirochete Borrelia burgdorferi and is transmitted via the bite of an infected tick. B. burgdorferi enters the skin, disseminates via the bloodstream, and infects various distal tissues, leading to inflammatory sequelae, such as Lyme arthritis and Lyme carditis.

Funder

Deborah and Mark Blackman-Global Lyme Alliance postdoctoral fellowship

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference53 articles.

1. Surveillance for Lyme disease—United States, 1992–2006;Bacon RM;MMWR Surveill Summ,2008

2. Epidemiology of Lyme Borreliosis

3. Lyme Disease—a Tick-Borne Spirochetosis?

4. The Spirochetal Etiology of Lyme Disease

5. Ticks and Lyme Disease in the United States

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