Invertase Production by Penicillium chrysogenum and Other Fungi in Submerged Fermentation

Author:

Poonawalla F. M.1,Patel K. L.1,Iyengar M. R. S.1

Affiliation:

1. Microbiological Research Laboratory, Alembic Chemical Works, Baroda, India

Abstract

A study was made of Penicillium chrysogenum and some other fungi to determine the relative distribution of intra- and extracellular invertase produced by them in submerged fermentation. The proportion of each type of enzyme varied with the organism and the period of fermentation. More of the enzyme initially bound to the mycelium was released into the medium with the progress of fermentation. Differences were observed in the effects of cultural conditions on enzyme production in P. chrysogenum and Saccharomyces cerevisiae . Considerably greater quantities of enzyme were produced by P. chrysogenum and the yeast in both laboratory and large-scale fermentors when sucrose was added continuously than when the same quantities of the sugar were added initially.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference19 articles.

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2. Enzymes of Aspergillus oryzae. III. The sequence of appearance and some properties of the enzymes liberated during growth;CREWTHER W. G.;Australian J. Biol. Sci.,1953

3. DAMLE S. P. K. SINGH AND D. GHOSH. 1958. Studies on soluble enzymes in penicillin fermentation broth. II. Invertase activity. Antibiotics Symposium Council of Scientific and Industrial Research New Delhi p. 137-144.

4. Penicillin production in cornsteep media with continuous carbohydrate addition;DAVEY V. F.;Appl. Microbiol,1953

5. Action of Penicillium chrysogenum on sucrose;DE ACCADIA F. D.;Rend. Ist. Super. Sanita,1955

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1. Penicillium chrysogenum as a fungal factory for feruloyl esterases;Applied Microbiology and Biotechnology;2023-01-03

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