Author:
Wiederhold Nathan P.,Fothergill Annette W.,McCarthy Dora I.,Tavakkol Amir
Abstract
ABSTRACTThein vitroactivities of luliconazole, amorolfine, ciclopirox, and terbinafine were determined against 320 dermatophyte isolates from large toenails of onychomycosis patients enrolled into an ongoing phase 2b/3 clinical study. The geometric mean MIC for luliconazole was 0.00022 μg/ml against all isolates, compared to 0.0194 to 0.3107 μg/ml for the three other agents. Thein vitropotency of luliconazole was maintained regardless of the dermatophyte species.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
26 articles.
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