SUMOylation- and GAR1-Dependent Regulation of Dyskerin Nuclear and Subnuclear Localization-Reference-Cited by-同舟云学术

SUMOylation- and GAR1-Dependent Regulation of Dyskerin Nuclear and Subnuclear Localization

Published:2021-03-24 Issue:4 Volume:41 Page:
ISSN:0270-7306
Container-title:Molecular and Cellular Biology
language:en
Short-container-title:Mol Cell Biol

Author:

MacNeil D. E.¹²,Lambert-Lanteigne P.¹,Qin J.¹²,McManus F. P.³,Bonneil E.³,Thibault P.³,Autexier C.¹²^ORCID

Affiliation:

1. Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montréal, Quebec, Canada

2. McGill University, Montréal, Quebec, Canada

3. Université de Montréal, Montréal, Quebec, Canada

Abstract

The nuclear and subnuclear compartmentalization of the telomerase-associated protein and H/ACA ribonucleoprotein component dyskerin is an important although incompletely understood aspect of H/ACA ribonucleoprotein function. Four SUMOylation sites were previously identified in the C-terminal nuclear/nucleolar localization signal (N/NoLS) of dyskerin.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Cell Biology,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/MCB.00464-20

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