Affiliation:
1. Department of Life Sciences, University of California, Riverside, California 92507
Abstract
In
Serratia marcescens
, the tryptophan biosynthetic enzymes were formed coordinately. A number of tryptophan auxotrophs showed single biochemical lesions; several mutants showed pleiotropic effects. Sucrose density gradient centrifugation revealed an unique pattern of migration of the tryptophan biosynthetic enzymes. The repression response of the
Serratia
enzymes to exogenous tryptophan was fivefold more sensitive than that found in
Escherichia coli
. When this information is contrasted with the available information on the other
Enterobacteriaceae
, one is compelled to conclude that
S. marcescens
enjoys a rather marked evolutionary divergence from the other enteric organisms.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
41 articles.
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