Inhibition of aminoglycoside activity in heparin-Reference-Cited by-同舟云学术

Inhibition of aminoglycoside activity in heparin

Published:1981-08 Issue:2 Volume:20 Page:155-158
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Nilsson L,Maller R,Anséhn S

Abstract

Measurements of aminoglycosides by an agar disk diffusion assay are inhibited by heparin in a dose-dependent way. When assayed by a homogeneous immunoassay, this was only evident for tobramycin. This indicates that specimens for aminoglycoside measurement should not be obtained in heparinized tubes. When heparin is used clinically as an anticoagulant, the amount in blood does not reach levels that affect the aminoglycoside activity.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.20.2.155

Reference8 articles.

1. New rapid bioassay of gentamicin based on Iuciferase assay of extracellular adenosine 5'-triphosphate in bacterial cultures;Nilsson L;Antimicrob. Agents Chemother.,1978

2. Factors affecting gentamicin assay;Nilsson L;Antimicrob. Agents Chemother.,1980

3. A rapid semi-automated bioassay of gentamicin based on Iuciferase assay of bacterial adenosine triphosphate;Nilsson L.;Scand. J. Infect. Dis.,1977

4. The elimination from plasna of intravenous heparin;Olsson P.;Acta Med. Scand.,1963

5. Heparn therpy and its laboratory control Br. J;Pitney W. IL;H"matol.,1970

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