Generation of Human Lung Organoid Cultures from Healthy and Tumor Tissue to Study Infectious Diseases-Reference-Cited by-同舟云学术

Generation of Human Lung Organoid Cultures from Healthy and Tumor Tissue to Study Infectious Diseases

Published:2022-04-13 Issue:7 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Salgueiro Lorena¹,Kummer Susann²,Sonntag-Buck Vera²,Weiß Anne²,Schneider Marc A.³⁴,Kräusslich Hans-Georg²,Sotillo Rocio¹⁴^ORCID

Affiliation:

1. Division of Molecular Thoracic Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany

2. Department of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany

3. Translational Research Unit, Thoraxklinik at Heidelberg University, Heidelberg, Germany

4. Translational Lung Research Center Heidelberg (TRLC), German Center for Lung Research (DZL), Heidelberg, Germany

Abstract

Three-dimensional (3D) human lung organoids reflect the native cell composition of the lung as well as its physiological properties. Human 3D lung organoids offer ideal conditions, such as timely availability in large quantities and high physiological relevance for reassessment and prediction of disease outbreaks of respiratory pathogens and pathogens that use the lung as a primary entry portal.

Funder

Deutsche Forschungsgemeinschaft

Deutsches Zentrum für Lungenforschung

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00098-22

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