Molecular and Physical Characterization of Burkholderia mallei O Antigens-Reference-Cited by-同舟云学术

Molecular and Physical Characterization of Burkholderia mallei O Antigens

Published:2002-02 Issue:3 Volume:184 Page:849-852
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Burtnick Mary N.¹,Brett Paul J.¹,Woods Donald E.¹

Affiliation:

1. Department of Microbiology and Infectious Diseases, University of Calgary Health Sciences Center, Calgary, Alberta, Canada T2N 4N1

Abstract

ABSTRACT Burkholderia mallei lipopolysaccharide (LPS) has been previously shown to cross-react with polyclonal antibodies raised against B. pseudomallei LPS; however, we observed that B. mallei LPS does not react with a monoclonal antibody (Pp-PS-W) specific for B. pseudomallei O polysaccharide (O-PS). In this study, we identified the O-PS biosynthetic gene cluster from B. mallei ATCC 23344 and subsequently characterized the molecular structure of the O-PS produced by this organism.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.184.3.849-852.2002

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