Role of Keratinocyte Injury in Adherence of Streptococcus pyogenes-Reference-Cited by-同舟云学术

Role of Keratinocyte Injury in Adherence of Streptococcus pyogenes

Published:1999-12 Issue:12 Volume:67 Page:6707-6709
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Darmstadt Gary L.¹²³,Mentele Laurel¹,Fleckman Philip²,Rubens Craig E.¹

Affiliation:

1. Divisions of Infectious Diseases1 and

2. Dermatology,2 Department of Pediatrics, Children's Hospital & Regional Medical Center, and

3. Division of Dermatology, Department of Medicine, University of Washington School of Medicine,3 Seattle, Washington 98105

Abstract

ABSTRACT Keratinocytes injured acutely by UVB light or lipopolysaccharide were used to test the hypothesis that keratinocyte injury promotes bacterial adherence and the development of group A streptococcal skin infections. Injury did not affect adherence to undifferentiated and differentiated keratinocytes, but keratinocyte differentiation promoted adherence four- to fivefold.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.67.12.6707-6709.1999

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