Gender-Related Cytokine Patterns in Sera of Schistosomiasis Patients with Symmers' Fibrosis-Reference-Cited by-同舟云学术

Gender-Related Cytokine Patterns in Sera of Schistosomiasis Patients with Symmers' Fibrosis

Published:2004-05 Issue:3 Volume:11 Page:627-630
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Silva-Teixeira David Nascimento¹,Contigli Cristiane¹,Lambertucci José Roberto²,Serufo José Carlos²,Rodrigues Virmondes¹

Affiliation:

1. Laboratory of Immunology, Faculdade de Medicina do TriÂngulo Mineiro, Uberaba

2. Departamento Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

Abstract

ABSTRACT Cytokine levels were compared between schistosomiasis patients affected by intense fibrosis defined by ultrasound examination and graded from F-0 to F-3. The concentrations of interleukin-1β (IL-1β), IL-4, IL-5, IL-10, IL-13, gamma interferon, and tumor necrosis factor alpha (TNF-α) were determined by enzyme-linked immunosorbent assay of serum samples. Levels of IL-4, IL-5, and TNF-α in the sera of F-3 patients were significantly higher than those found in F-0 individuals, while levels of IL-13 were lower. Levels of IL-4, IL-5, and TNF-α in serum were significantly higher in F-3 males than in F-0 males or F-3 females. Conversely, levels of IL-13 were significantly lower in F-3 females than in F-0 females and males.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CDLI.11.3.627-630.2004

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