Dissemination of Macrolide-Resistant Streptococcus pneumoniae Isolates Containing Both erm (B) and mef (A) in South Korea

Author:

Waites Ken B.12,Jones Kellie E.2,Kim Kyung Hyo13,Moser Stephen A.12,Johnson Crystal N.2,Hollingshead Susan K.2,Kang Eun-Suk4,Hong Ki Sook4,Benjamin William H.12

Affiliation:

1. Departments of Pathology

2. Microbiology, University of Alabama at Birmingham, Birmingham, Alabama

3. Pediatrics

4. Laboratory Medicine, College of Medicine, Ewha Woman's University, Seoul, South Korea

Abstract

ABSTRACT Macrolide resistance was detected in 64 of 77 (83.1%) Streptococcus pneumoniae isolates from South Korea. Seven (10.9%) isolates contained only mef (A), 32 (50%) contained only erm (B), and 25 (39.1%) contained mef (A) and erm (B). Nineteen isolates containing mef (A) and erm (B) belonged to serotype 19F, and seven isolates were identical to the Taiwan 19F -14 clone.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference16 articles.

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3. Macrolide Resistance by Ribosomal Mutation in Clinical Isolates of Streptococcus pneumoniae from the PROTEKT 1999-2000 Study

4. Farrell, D. J., I. Morrissey, S. Bakker, and D. Felmingham. 2002. Molecular characterization of macrolide resistance mechanisms among Streptococcus pneumoniae and Streptococcus pyogenes isolated from the PROTEKT 1999-2000 study. J. Antimicrob. Chemother.50(Suppl. S1):39-47.

5. Felmingham, D., R. R. Reinert, Y. Hirakata, and A. Rodloff. 2002. Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study, and compatative in vitro activity of the ketolide, telithromycin. J. Antimicrob. Chemother.50(Suppl. S1):25-37.

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