Risk of Fungemia Due to Rhodotorula and Antifungal Susceptibility Testing of Rhodotorula Isolates

Author:

Zaas Aimee K.12,Boyce Molly1,Schell Wiley1,Lodge Barbara Alexander12,Miller Jackie L.1,Perfect John R.12

Affiliation:

1. Duke University Mycology Research Unit

2. Division of Infectious Diseases and International Health, Department of Internal Medicine, Duke University Medical Center, Durham, North Carolina 27705

Abstract

ABSTRACT Rhodotorula infections occur among patients with immunosuppression and/or central venous catheters. Using standardized methods (NCCLS M27-A), we determined the antifungal susceptibilities of 10 Rhodotorula bloodstream infection isolates. Patient information was collected for clinical correlation. The MICs of amphotericin B and posaconazole were the lowest, and the MICs of triazoles and echinocandins were higher than those of other antifungal agents.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference16 articles.

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2. Eisenberg, E. S., B. E. Alpert, R. A. Weiss, N. Mitman, and R. Soeiro. 1983. Rhodotorula rubra peritonitis in patients undergoing continuous ambulatory peritoneal dialysis. Am. J. Med.75:349-352.

3. Rhodotorula glutinis -Related Meningitis

4. Naveh, Y., A. Friedman, D. Merzbach, and N. Hashman. 1975. Endocarditis caused by Rhodotorula successfully treated with 5-flucytosine. Br. Heart J.37:100-104.

5. National Committee for Clinical Laboratory Standards. 1997. Reference method for broth dilution antifungal susceptibility testing of yeasts. M27-A. National Committee for Clinical Laboratory Standards Wayne Pa.

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