Morphogenesis of Bullet-Shaped Rabies Virus Particles Regulated by TSG101

Author:

Itakura Yukari1,Tabata Koshiro1,Saito Takeshi2,Intaruck Kittiya1,Kawaguchi Nijiho1,Kishimoto Mai1,Torii Shiho1,Kobayashi Shintaro3,Ito Naoto4,Harada Michiko5,Inoue Satoshi5,Maeda Ken5,Takada Ayato26ORCID,Hall William W.789,Orba Yasuko1810,Sawa Hirofumi189610,Sasaki Michihito110ORCID

Affiliation:

1. Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Hokkaido, Japan

2. Division of Global Epidemiology, International Institute for Zoonosis Control, Hokkaido University, Hokkaido, Japan

3. Laboratory of Public Health, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan

4. Laboratory of Zoonotic Diseases, Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan

5. Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, Japan

6. One Health Research Center, Hokkaido University, Hokkaido, Japan

7. National Virus Reference Laboratory, School of Medicine, University College of Dublin, Dublin, Ireland

8. International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Hokkaido, Japan

9. Global Virus Network, Baltimore, Maryland, USA

10. Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Hokkaido, Japan

Abstract

Enveloped viruses bud from cells with the host lipid bilayer. Generally, the membrane modulation and abscission are mediated by host ESCRT complexes.

Funder

MEXT | Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Health Labour Sciences Research

World-leading Innovative and Smart Education Program

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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